illustration (IMAGE) UT Southwestern Medical Center Caption Immunofluorescent staining of Npc1-deficient mouse cerebellum, with Purkinje neurons in red, activated microglia in green and nucleus in blue. Massive microglia infiltration and loss of Purkinje neurons cause severe neurological disease in Niemann-Pick disease type C. Credit Ting-Ting Chu Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.