How the Ubiquitin Ligase RFWD3 Works (IMAGE) University of Würzburg Caption A: The enzyme RFWD3 helps target other proteins on single-stranded DNA for degradation. B: Cells lacking RFWD3 show DNA repair defects. Credit (Figure modified from Inano et al.) Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.