Cause of Statin-Induced Myopathies (IMAGE)

Cell Press

Cause of Statin-Induced Myopathies

Caption

Statin-induced myopathies are the most common side effects of these widely used cholesterol-lowering drugs, affecting millions of patients. Schirris et al. identified the Qo site of mitochondrial complex III as off-target of statin lactones and show possible mechanisms for the attenuation of their inhibitory effect.

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Schirris et al./<em>Cell Metabolism</em> 2015

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