Cryo-EM 3D (IMAGE) University of Michigan Caption The cryo-EM 3D reconstruction (left) of the protein P-Rex1 bound to G??? and the protein model (right) showing that G?? (top; blue and green) binds to a compact, multi-domain surface on P-Rex1 (bottom; yellow, magenta, teal and gold). Credit Jennifer Cash, U-M Life Sciences Institute. Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.