Cytosine, But Not Adenine, Base Editors Induce Genome-Wide Off-Target Mutations In Rice (IMAGE)

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Cytosine, But Not Adenine, Base Editors Induce Genome-Wide Off-Target Mutations In Rice

Caption

(A) Experimental design and work flow. (B) Comparison of total C>T SNVs in the BE3, HF1-BE3, ABE and control plants. (C) Comparisons of C>T SNVs in the given regions versus in the whole genome among BE3, HF1-CBE, ABE and control groups of plants. (D) C>T SNVs in highly transcribed regions versus in the whole genome among BE3, HF1-BE3, ABE and control groups of plants.

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