Restoring Nerve Insulation (IMAGE) Cincinnati Children's Hospital Medical Center Caption This image from a paper in Nature Medicine shows how inhibiting an enzyme called HDAC3 in mice increases the expansion of Schwann cells (green). Schwann cells form a protective insulating layer called the myelin sheath around the nerves. Blocking HDAC3 increases the production of myelin proteins, shown in red. Scientists from Cincinnati Children's tested an experimental molecular therapy in mice that restored nerve insulation and improved limb function following nerve injury. Credit Cincinnati Children's Usage Restrictions Please credit Cincinnati Children's License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.