Confocal Image (IMAGE) University of Helsinki Caption This is a confocal image of a 3-D fibrin assay of the WM852 melanoma cells first co-cultured with lymphatic endothelial cells (LECs). LEC contact induces melanoma cells to an invasive sprouting growth phenotype. GFP expressing (green) melanoma cells were stained with anti-CD44 antibodies (red), nuclei are counterstained with Hoechst 33342 (blue). Credit Päivi Ojala Lab/University of Helsinki Usage Restrictions The image may only be used with appropriate caption and credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.