Nuclear localization of YAP and RUNX2 (IMAGE)

Tokyo Metropolitan University

Nuclear localization of YAP and RUNX2

Caption

(top) Intracellular localization of RUNX2 and YAP in MSCs on gelatin gels with different elastic moduli. Notice how more signal is seen in a single location (the nucleus) for stiffer substrates. (bottom) Illustration of how localization of YAP and RUNX2 changes with substrate stiffness for different batches. Note the consistency between batches in how YAP localization changes with stiffness, and the lack thereof for RUNX2 before they converge.

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Tokyo Metropolitan University

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