TET1's Role in Myelin Formation (IMAGE)

Advanced Science Research Center, GC/CUNY

TET1's Role in Myelin Formation

Caption

In young adult mice (left), TET1 is active in oligodendroglial cells especially after injury and this leads to new myelin formation and healthy brain function. In old mice (right), the age-related decline of TET1 levels impairs the ability of oligodendroglial cells to form functional new myelin. The authors are currently investigating whether increasing TET1 levels in older mice could rejuvenate the oligodendroglial cells and restore their regenerative functions.

Credit

Sarah Moyon

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