Ouch! (IMAGE) Brown University Caption Overall, emergency patients given NSAID painkillers were no more likely to report persistent pain six weeks after a car crash than comparable patients given opioids. But the opioids were more likely to still be in use, raising concerns about dependence. Credit Pixabay Usage Restrictions with credit License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.