STAT5B as a Potential Target for Anti-Cancer Medication (IMAGE)

University of Veterinary Medicine -- Vienna

STAT5B as a Potential Target for Anti-Cancer Medication

Caption

a) Patients with an activating STAT5B mutation display a suppressed interferon response, which promotes the development and growth of leukemia cells. b) In the STAT5B-deficient leukemia mouse model, the increased interferon response led to a suppression of malignant leukemia cells. This reveals STAT5B as a potential target for anti-cancer medication.

Credit

Institute of Pharmacology and Toxicology/Vetmeduni Vienna

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