Non-B DNA in great apes (IMAGE)
Caption
New research predicts the location of DNA sequences that can form structures besides the canonical double helix — non-B DNA — in the recently released telomere-to-telomere genomes of the great apes, finding that non-B DNA is enriched in newly deciphered genomic regions, including telomeres and centromeres. Image shows evolutionary relationships among the great apes (left) including chimpanzee, bonobo, human, gorilla, and two orangutan species (from top to bottom), and illustrations of representative chromosomes (right) with canonical helical and non-B DNA.
Credit
Dani Zemba and Makova laboratory, Penn State
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