Molecular docking of the main components of HXTL and pathway-related proteins (IMAGE)

Xia & He Publishing Inc.

Molecular docking of the main components of HXTL and pathway-related proteins

Caption

(a–c) The 3D visualization of molecular docking modes of HXTL’s top four active components (luteolin, beta-sitosterol, stigmasterol, quercetin) and top three HXTL-PMOP targets (IL6, AKT1, PI3K). (d) The docking mode of HXTL with NFATc1. (e) Docking and binding energy of the active ingredient of the core drug combination with the key target protein molecule. AKT1, AKT serine/threonine kinase 1; HXTL, Huo Xue Tong Luo; IL, interleukin; NFATc1, nuclear factor of activated T Cells 1; PMOP, postmenopausal osteoporosis.

Credit

Yamei Liu, Liangliang Xu, Qiangqiang Zhao,

Usage Restrictions

Credit must be given to the creator. Only noncommercial uses of the work are permitted.

License

CC BY-NC

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.