Kidney micrographs (IMAGE)
Caption
(a) Control; (b, c) Treatment with ACV (150 mg/kg); (d, e, f) Supplementation with NAC (25 mg/kg), NAC (50 mg/kg), and NAC (100 mg/kg), respectively. R, normal renal tubule; N, tubular necrosis; G, normal glomerulus; M, mesangial proliferation; C, collapsed glomerulus; W, widened Bowman’s space. H and E × 400.
This study demonstrated that NAC supplementation prevented ACV-induced nephrotoxicity in rats in a dose-dependent manner, indicating potential therapeutic value for ACV-associated nephrotoxicity.
Credit
Elias Adikwu,
Usage Restrictions
Credit must be given to the creator. Only noncommercial uses of the work are permitted.
License
CC BY-NC