Quality Control Spliceosome (IMAGE)

Heidelberg University

Quality Control Spliceosome

Caption

Aided by two molecular control factors, the spliceosome rejects pre-mRNA that could be incorrectly spliced. While GPATCH1 detects the defective pre-mRNA, DHX35 removes it from the spliceosome, which is subsequently disassembled and made available for a new round of splicing.

Credit

© Paulina Fischer

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