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Image 1: MTT, lactate dehydrogenase, and caspase assay results after treatment with OR3 pigment from Streptomyces coelicolor in MDA-MB-231 cells. The effect of OR3 pigment on (A) MDA-MB-231 cells and (B) HEK-293 cells at 24, 48, and 72 h using MTT assays. (C) Lactate dehydrogenase activity in MDA-MB-231 cells treated with OR3 pigment (8 μg/mL). (D) Caspase 9 activity. The data are expressed as mean ± SE and analyzed by one-way ANOVA analysis. *P<0.05 and ***P<0.001 compared with the control. Dox: doxorubicin; C: control.

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Somasekhara Derangula, Varalakshmi K Nadumane

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