Cysteinyl leukotriene receptor 1 modulates retinal immune cells, vascularity and proteolytic activity in aged mice (IMAGE)
Caption
Figure 9. Proteasome activity in retinal lysates of young untreated, vehicle-treated and MTK-treated old mice. Retinal lysates were incubated for 120 minutes with the substrate Z-Gly-Gly-Leu-AMC at RT, and the fluorescence intensity (RFU) of the liberated AMC was measured every 15 minutes. MG-132 is a proteasome inhibitor and served as an assay control (n = 2). The values are represented as the mean ± SEM, n = 7–8. Two-way ANOVA (main factors: group and time) followed by a Dunnett multiple comparison test. ###p < 0.001, young control group vs. old vehicle-treated group; ****p < 0.0001, old MTK-treated group vs. old vehicle-treated group.
Credit
Copyright: © 2025 Koller et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Usage Restrictions
With credit to the original source.
License
Original content