Sex differences of chronic jet lag in mice (IMAGE)
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Chronic jet lag affects male and female mice in different ways, according to a new study by Kyushu University researchers. Jet-lagged male mice gain weight and have a lower glucose tolerance, while female mice lose weight compared to controls, and their glucose tolerance remains unchanged. In males, the body clock is more resilient to jet lag, showing little change in clock gene activity in the liver and adrenal glands, or in the rhythm of deep body temperature. Female mice are more vulnerable to jet lag, with significant changes in clock genes and their body temperature rhythm.
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Shinobu Yasuo, Kyushu University
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