Analyzing the binding affinity of natural compounds to SARS-CoV-2 spike proteins (IMAGE)

Nara Institute of Science and Technology

Analyzing the binding affinity of natural compounds to SARS-CoV-2 spike proteins

Caption

(A) A comprehensive analysis of caffeine binding to one of the spike proteins; (B, C) Caffeine interacts with critical amino acids in the SARS-CoV-2 S protein’s receptor-binding domain (RBD), specifically CYS432, CYS379, TYR365, and PRO384; (D) The bioavailability radar of caffeine shows its drug-likeness properties.

Credit

Md. Altaf-Ul-Amin from Nara Institute of Science and Technology, Japan

Usage Restrictions

Cannot be used without permission.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.