NKD2 in BMSCs facilitated osteoblast differentiation and suppressed adipocyte formation in OVX mice. (IMAGE)

Chongqing Medical University

NKD2 in BMSCs facilitated osteoblast differentiation and suppressed adipocyte formation in OVX mice.

Caption

NKD2 in BMSCs facilitated osteoblast differentiation and suppressed adipocyte formation in OVX mice. Representative images of immunohistochemical staining of ALP are shown (A). The number of osteoblasts was quantified (B). Representative images of hematoxylin and eosin staining are shown (C). The number (D) and area (E) of adipocytes were quantified. Representative images of immunohistochemical staining of TSC1 are shown (F). The number of TSC1-positive cells on the trabeculae was counted (G). Scale bar in (A, F): 20 μm. Scale bar in (C): 200 μm. The values were expressed as mean ± standard deviation; n = 8. ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001. ns, no significance; NKD2, naked cuticle homolog 2; BMSCs, bone marrow mesenchymal stem cells.

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Genes & Diseases

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