Figure 1: Mechanism of synthetic mRNA in enhancing immune cell activity against metastasizing cancer cells (IMAGE)
Caption
Immune cells (NK and cytotoxic T cells) are activated by short-synthetic mRNA which binds to the ZC3H12D receptor and is transported to the nucleus where it induces the expression of GZMB, a key molecule for tumor-killing activity.
Credit
Professor Sachie Hiratsuka, Shinshu University School of Medicine
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