Metabolic dysfunction-associated steatohepatitis pathogenesis: An intricate interplay of cellular processes (IMAGE)

Waseda University

Metabolic dysfunction-associated steatohepatitis pathogenesis: An intricate interplay of cellular processes

Caption

Nwd1 deletion disrupts sarco/endoplasmic reticulum calcium ATPase (SERCA2) activity, which leads to heightened endoplasmic reticulum stress, contributing to metabolic dysfunction-associated steatohepatitis pathological development.

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Professor Shin-ichi Sakakibara from Waseda University, Japan

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