Schematics illustrating the mechanism of our acoustofluidics-based intracellular delivery device. (IMAGE)
Caption
(a) Device schematic. (b) Cross-sectional view of the device for illustrating the generation of standing bulk acoustic waves with a pressure node at the top capillary wall, which can push a cell loaded in the capillary to the top wall. (c) Illustration of the cell movement in a capillary coated with cargo-encapsulated nanoparticles under continuous flow and acoustic waves. The acoustic waves can push cells to the top wall, enabling controllable contact between cells and nanoparticles when the cells flow through the capillary along its top wall. (d) A schematic illustrating the intracellular cargo delivery process.
Credit
Zhishang Li et al.
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