Role of dorsal anterior cingulate cortex (dACC) to dorsolateral prefrontal cortex (dlPFC) connectivity in relation to the onset of substance use (IMAGE)
Caption
A. Seed region: dorsal anterior cingulate cortex (dACC). B. Whole-brain regression analysis reveals an association between higher dACC-dlPFC connectivity at Time 1 and a delayed age of first substance use. C. Orange data points show the trajectory of dACC-dlPFC connectivity before substance use onset, with a decline observed one year prior. Gray data points represent dACC-dlPFC connectivity at and after substance use onset. Error bars indicate the standard error.
Credit
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, Chen et al.
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CC BY-NC-ND