Ebola virus vs. mAb 3A6 (IMAGE)
Caption
The model on the left shows how the Ebola virus stalk has a compact conformation, which blocks the site where mAb 3A6 would bind. The model on the right shows how this portion of the stalk can adopt an extended, or lifted, conformation, which would allow mAb 3A6 to access its binding domain.
Credit
Saphire Lab, published in Nature Communications, January 2025.
Usage Restrictions
Credit: Saphire Lab, published in Nature Communications, January 2025.
License
Original content