BTZ-043 Press release image (IMAGE)
Caption
Granuloma structure and distribution of the antibiotic BTZ-043 in differently stained tissue sections of two tuberculosis granulomas. The stains show (in z-shaped order from top left to bottom right): the necrotic granuloma centers, connective tissue capsules, immune cell layers and the accumulation of BTZ-043 in the entire granulomas.
Credit
CC BY 4.0/Images modified from: Römpp, A., Treu, A., Kokesch-Himmelreich, J. et al. The clinical-stage drug BTZ-043 accumulates in murine tuberculosis lesions and efficiently acts against Mycobacterium tuberculosis. Nat Commun 16, 826 (2025). https://doi.org/10.1038/s41467-025-56146-9.
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License
CC BY