ELK3 inhibits its transcriptional activity by binding to the kelch-like ECH-associated protein 1 (Keap1) promoter, affecting the expression of ferroptosis-related molecules (IMAGE)
Caption
NAD(P)H quinone dehydrogenase 1 (NQO1), solute carrier family 7 member 11 (SLC7A11), and nuclear factor erythroid 2-related factor 2 (Nrf2), and involved in the progression of ferroptosis in rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS).
Credit
Jihong Pan, Yaqun Zhang, Huimin Shi
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CC BY-NC