Graphical Abstract (IMAGE)

Shanghai Jiao Tong University Journal Center

Graphical Abstract

Caption

  • The discovery of G protein-coupled receptor (GPCR) heteromers has revealed a new level of complexity in their functional characteristics.

  • This review explores a variety of methodologies and live cell imaging technologies for the investigation of physical interactions in GPCR heteromers and their functional alterations.

  • Live cell imaging technologies such as fluorescent protein-based biosensors promise a deeper understanding of GPCR heteromers, urging a reassessment of their physiological importance and pharmacological relevance.

Credit

All authors (Hyunbin Kim, Huimin Lee & Jihye Seong)

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License

CC BY-NC-ND

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