mouse liver (IMAGE)

University of California - San Diego

mouse liver

Caption

These images show slices of mouse liver under the microscope, with tumors outlined in yellow and green indicating the expression of different proteins within cells. The left column is a control group. In the center column, the protein detected (TBG-Cre) is expressed in all liver cells, so the entire image appears green. In the right column, the protein detected (p21-Cre) is only expressed in senescent liver cells. Because green is only visible within the tumor area, the results show that liver tumors originate from previously senescent liver cells.

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UC San Diego Health Sciences

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