Pathway to Trans-differentiated Cardiomyocyte Maturation (IMAGE)

Korea University College of Medicine

Pathway to Trans-differentiated Cardiomyocyte Maturation

Caption

This diagram illustrates how the combination of fibroblast growth factor 4 and ascorbic acid activates the JAK2–STAT3 signaling pathway, promoting the maturation of induced cardiomyocytes (iCMs). This approach effectively reprograms fibroblasts into cardiomyocytes with improved structure and function, offering exciting possibilities for regenerative medicine.

Credit

The authors

Usage Restrictions

Cannot be reused without permission

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.