immunofluorescence image (IMAGE)

Memorial Sloan Kettering Cancer Center

immunofluorescence image

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An immunofluorescence image of an aged mouse liver. Expression of β-galactosidase (white) and uPAR (yellow) in senescent cells serve as target for engineered CAR T cells. Elimination of these cells improved age-related metabolic dysfunction.

The ability to improve age-related metabolic dysfunction by targeting senescent cells with engineered CAR T cells was just one of many discoveries made by MSK researchers in 2024.

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Memorial Sloan Kettering Cancer Center

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