Mechanism of action of dinuclear platinum(II) complexes (IMAGE)

Shibaura Institute of Technology

Mechanism of action of dinuclear platinum(II) complexes

Caption

The dinuclear platinum(II) complexes inhibit prostate cancer cell growth by binding to the androgen receptor (AR) and disrupting AR-mediated gene expression. This mechanism leads to apoptosis and prevents dihydrotestosterone (DHT)-induced cell proliferation.

Credit

Yoshihisa Hirota from SIT, Japan Source: https://doi.org/10.1021/acs.inorgchem.4c01093

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License

CC BY

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