ROS-mediated epigenetic reprogramming regulates tumor metastasis (IMAGE)

Sichuan International Medical Exchange and Promotion Association

ROS-mediated epigenetic reprogramming regulates tumor metastasis

Caption

During the process of metastasis, tumor cells inevitably encounter the stimulation of various oxidative stressors, resulting in the fluctuation of intracellular reactive oxygen species (ROS) levels. Epigenetic reprogramming serves as a bridge between oxidative stress and tumor metastasis. In different stages of metastasis, ROS can modulate tumor behavior by reprogramming DNA methylation, histone modification, noncoding RNA (ncRNA), and N6-methyladenosine (m6A) modification.

Credit

Yunlong Lei

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