Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin (IMAGE)

Mass General Brigham

Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin

Caption

Papillomavirus-induced immune response blocks the expansion of mutant cells in sun-damaged skin. A large collection of mutant cells in ultraviolet-radiated skin without papillomavirus colonization (left) compared with a small number of mutant cells surrounded by immune cells in papillomavirus-colonized skin (right). Memory T cells (red), killer T cells (yellow), and mutant skin cells (cyan).  

Credit

Dr. Heehwa Son, Demehri lab, Massachusetts General Hospital

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Reporters may use this image in news coverage of the authors' publication in Cancer Cell

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