New Study Finds Neurobiological Evidence of Peripartum Depression in Women, Distinguishing It from Major Depressive Disorder (IMAGE)

Elsevier

New Study Finds Neurobiological Evidence of Peripartum Depression in Women, Distinguishing It from Major Depressive Disorder

Caption

A) Glass brain rendering of significant right basal ganglia cluster. B) Slices of the brain showing significant right brain cluster. C) Model of the moderation analysis with peripartum depression (PPD) moderating the association between estradiol polygenic risk scores (PRSs) and grey matter volumes. D) Partial least squares regression results with the 11 PRSs for estradiol entered as predictors for extracted significant right basal ganglia cluster. Three PRSs were selected as significant in contributing to explain variance in cluster volumes. E) Graph showing individual effects of the estradiol PRSs on cluster volumes in the PPD group and no PPD group.

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Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

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