Fig. (IMAGE) Osaka University Caption Loss of ARMC5 disrupts the balance of saturated and unsaturated fatty acids through accumulation of SCAP-free SREBF1. Credit 2024 Okuno et al., ARMC5 selectively degrades SCAP-free SREBF1 and is essential for fatty acid desaturation in adipocytes., Journal of Biological Chemistry Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.