Brain aging and Alzheimer’s disease, a perspective from non-human primates (IMAGE)
Caption
Figure 1. Aged cynomolgus monkey. Cerebral amyloid angiopathy involves blood vessels of the meninge (A), frontal cortex (FC), parietal cortex (Par C), and amygdala (Amyg) with additional β-amyloid (Aβ) deposition in the perivascular spaces. In contrast with the extensive cerebral amyloid angiopathy, a few neurons containing hyper-phosphorylated tau (antibody AT8) are scattered in the frontal and parietal cortex, and hippocampus. Paraffin sections slightly counterstained with haematoxylin. Upper two rows, bar = 180 μm; lower row, bar = 25 μm.
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2024 Isidro
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