A monoclonal antibody that targets the nitration sites of hepatocyte growth factor (HGF) (IMAGE)

Kyushu University

A monoclonal antibody that targets the nitration sites of hepatocyte growth factor (HGF)

Caption

HGF nitration disrupts muscle homeostasis as an organism age. The new rat anti-HGF monoclonal antibody the research team developed, called 1H41C10, specially binds to the nitration sites of HGF and blocks nitration. The team hopes that this can eventually lead to therapies that can treat age-related muscle atrophy and impaired muscle regeneration.

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Kyushu University/Tatsumi lab

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