Splicing with USP39 (IMAGE) Goethe University Frankfurt Caption USP39 stabilizes the spliceosome (green), which cuts out unneeded parts (grey and purple) of the mRNA. If USP39 is missing, some of the mRNA is poorly processed. This results in misfolded proteins, which lead to stress and cell death. Credit Molecular Signaling Group, IBC2, Goethe University Frankfurt Usage Restrictions To be used only when reporting on Goethe University Frankfurt. Give credit to Molecular Signaling Group, IBC2, Goethe University Frankfurt License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.