Workflow of ImSpiRE (IMAGE) Science China Press Caption ImSpiRE enhances spatial resolution in three steps: it first extracts image features from spots and patches based on histological images, then computes the relationships between spots and patches, and finally redistributes gene expression data across patches using an optimal transport method. This process produces enhanced transcriptional profiles with higher resolution. Credit ©Science China Press Usage Restrictions Use with credit. License Original content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.