Shoji-ISGylation-Illustration (IMAGE)
Caption
A section of Goodsell et al.’s magnificent “Integrative illustration for coronavirus outreach” highlighting the packaging of the viral genetic material (in pink) by the scaffold “nucleocapsid protein” (in light purple). The cell’s immune system attaches a tag (not pictured) to this protein, disabling its ability to form aggregates and thus preventing the virus from being assembled. However, the novel coronavirus has an enzyme (not highlighted) that can remove the tag and thus evade the innate immune system’s defense mechanism.
Credit
2020 Goodsell et al., DOI: 10.1371/journal.pbio.3000815
Usage Restrictions
Credit must be given to the creator.
License
CC BY