Mechanisms of miRNA in Cancer Development (IMAGE)

Sichuan International Medical Exchange and Promotion Association

Mechanisms of miRNA in Cancer Development

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A. miRNAs are cut in the nucleus, sent to the cytoplasm, and processed there to control certain mRNAs. They can also move between cells in tiny bubbles to regulate them. B. miRNA can act as both oncomiRs and tumor suppressors, affecting cancer through various pathways. C. miRNA and epigenetic effects interact to form a miRNA-epigenetic feedback loop, whose dysregulation is closely related to cancer development. D. miRNA dysregulation forms a complex tumorigenic symbiosis with tumor cells and the tumor microenvironment, especially affecting immune cells. Photo credit: Shiwei Duan.

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Shiwei Duan

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