A dendrite – an extension of a neuron - from a 12-month-old human cerebral cortex neuron, grown from human stem cells and transplanted into a mouse cerebral cortex. (IMAGE)
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A dendrite – an extension of a neuron - from a 12-month-old human cerebral cortex neuron, grown from human stem cells and transplanted into a mouse cerebral cortex. Two human-specific genes, SRGAP2B and SRGAP2C, were turned off, causing the neuron’s synapses to mature faster. The number of small protrusions on the dendrite, called dendritic spines, resembles what is typically seen in a five to ten-year-old child.
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@Baptiste Libé-Philippot, 2024
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