High-affinity anti- CADM1 antibody suppresses neuronal signals produced in response to pain stimulus (IMAGE)

Kindai University

High-affinity anti- CADM1 antibody suppresses neuronal signals produced in response to pain stimulus

Caption

Femtosecond laser-induced pain stimulation of dorsal root ganglion neurite induces signal conduction along the nerve fiber leading to the perception of pain. CADM1 expressed on the nerve cell, when bound by high affinity antibody A, fails to conduct the pain signal, and suppresses the perception of pain.

Credit

Professor Akihiko Ito from Kindai University Faculty of Medicine

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