Dana-Farber Research: Antibody-drug conjugate found effective against brain metastases in patients with HER2-positive breast cancer (IMAGE)
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A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. The findings, from an international clinical trial led by Dana-Farber Cancer Institute researchers, reinforce earlier findings of the benefits of the drug – trastuzumab deruxtecan (T-DXd), an antibody-drug conjugate – in these patients, trial leaders say.
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Dana-Farber Cancer Institute
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