Leukocyte telomere length and attrition in association with disease severity in cystic fibrosis patients (IMAGE)

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Leukocyte telomere length and attrition in association with disease severity in cystic fibrosis patients

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Figure 2. Difference in age-dependent leukocyte telomere length change from timepoint 1 to timepoint 2 in ΔF508 homozygous vs. heterozygous. Non-linear (quadratic) association of age with the LTL attrition in CF patients homozygous for the ΔF508 mutation (n=44) compared with heterozygous patients (n=41) P-interaction between the quadratic term of age at TP1 and genotype (P=0.044), reflecting the genotype-specific non-linear LTL attrition-age association. Abbreviations: TP1: timepoint 1; TP2: timepoint 2; LTL: leukocyte telomere length.

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© 2024 Martens et al.

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