Role of Sae2 protein in regulating nuclease activity during yeast DNA repair. (IMAGE)

Kindai University

Role of Sae2 protein in regulating nuclease activity during yeast DNA repair.

Caption

Homologous recombination is a DNA repair mechanism that counteracts double-stranded breaks in DNA. Researchers at Kindai University have recently revealed how the Sae2 protein coordinates with the Mre11-Rad50-Xrs2 complex to activate endonuclease and 3'-5' exonuclease during DNA end resection in budding yeast.

Credit

Prof. Miki Shinohara from Kindai University

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