Schematic diagram of MT in GBM. (IMAGE) China Anti-Cancer Association Caption Schematic diagram of MT in GBM. Under the influence of many regulators represented by NF-κB, as well as many microenvironmental factors such as hypoxia, exosomes, and macrophages, GBM cells undergo mesenchymal transformation. Credit Cancer Biology & Medicine Usage Restrictions Credit must be given to the creator. License CC BY Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.