Polyunsaturated fatty acids and its association with autism spectrum disorder (ASD) (IMAGE)

University of Fukui

Polyunsaturated fatty acids and its association with autism spectrum disorder (ASD)

Caption

Arachidonic acid, which is released from phospholipid membranes, is metabolized to various epoxyeicosatrienoic acid (EET) compounds and subsequently to dihydroxyeicosatrienoic acids (diHETrE). This study revealed that high levels of 11,12- diHETrE in umbilical cord blood are associated with ASD symptoms, such as social affect (SA) and adaptive functioning. Additionally, lower levels of 8,9-diHETrE impacted repetitive/restrictive behaviors (RRB).

Credit

Hideo Matsuzaki from University of Fukui

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License

CC BY

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