Amyloid beta plaque in neurons modeling late-onset Alzheimer's disease (IMAGE)

WashU Medicine

Amyloid beta plaque in neurons modeling late-onset Alzheimer's disease

Caption

Researchers at Washington University School of Medicine in St. Louis have developed a way to study aged neurons in the lab without a brain biopsy, allowing them to accurately model the effects of aging in the development of late-onset Alzheimer's disease. Shown is a 3D reconstruction of amyloid beta plaque deposition (green) between neurons (red) grown in the lab. These neurons were transformed from human skin cells taken from patients with late-onset Alzheimer's disease.

Credit

ANDREW YOO, ZHAO SUN

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